Clinical Efficacy of Bisoprolol on 32 Cases Chronic Congestive Heart Failure

Objective To investigate the clinical efficacy of highly selective β-blocker bisoprolol on chronic congestive heart failure. Methods Sixty four patients with chronic congestive heart failure were selected. Thirty two patients were treated with bisop rolol incombination with the base of routine therapy including digitalis,diuretics. Heart rate,blood pressure,echocardiography and exercise tolerance test. Results The total effective rate of treatment group is 81.25%,the total effective rate of control group 65.63%. There was a significant difference between two groups(P0.05). Bisoprolol in addition to routine anti heart failure therapy could significantly improve cardiac functional class,reduce heart rate decrease systolic and diastolic blood pressure. And increase the LVEF. LVESVI and LVEDVI of the bisoprolol group are significantly decreased. Exercise tolerance compared with the control group improved significantly(P0.01). Conclusion On the basis of routine anti heart failure drug therapy,bisoprolol could significantly imp rove the efficacy.