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2012•ACTA AGRICULTURAE UNIVERSITATIS JIANGXIENSISRequires access

Experimental Study on Anti-tumor Effects of Scutellaria barbata D.Don Polyaccharides in Vivo

Xiujuan Zhang

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Abstract

Objective:To study the purifying method for Scutellaria barbata D.Don polyaccharides(SPS) and its anti-tumor effect of SPS in entrails.Methods: Using Sevag and Phenol-sulfuric acid method the content of polysaccharide was determined;the anti-tumor effect of SPS and the spleen index and the thymus index were observed by tumor transplant experiment on animal.Results:SPS can inhibite the growth of S180 and the effect on middle dose group was the best;the spleen index was affected remarkably in every group and the thymus index was inhibited by big dose(200 mg/kg).Conclusion:The content of polysaccharide purified with Sevay method and the polysaccharide content in crude polysaccharide were significantly different;the method is practical;SPS has anti-tumor effect and can improve immunity.

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What this paper is about

Objective:To study the purifying method for Scutellaria barbata D.Don polyaccharides(SPS) and its anti-tumor effect of SPS in entrails.Methods: Using Sevag and Phenol-sulfuric acid method the content of polysaccharide was determined;the anti-tumor effect of SPS and the spleen index and the thymus index were observed by tumor transplant experiment on animal.Results:SPS can inhibite the growth of S180 and the effect on middle dose group was the best;the spleen index was affected remarkably in every group and the thymus index was inhibited by big dose(200 mg/kg).Conclusion:The content of polysaccharide purified with Sevay method and the polysaccharide content in crude polysaccharide were significantly different;the method is practical;SPS has anti-tumor effect and can improve immunity.

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Available abstract

Objective:To study the purifying method for Scutellaria barbata D.Don polyaccharides(SPS) and its anti-tumor effect of SPS in entrails.Methods: Using Sevag and Phenol-sulfuric acid method the content of polysaccharide was determined;the anti-tumor effect of SPS and the spleen index and the thymus index were observed by tumor transplant experiment on animal.Results:SPS can inhibite the growth of S180 and the effect on middle dose group was the best;the spleen index was affected remarkably in every group and the thymus index was inhibited by big dose(200 mg/kg).Conclusion:The content of polysaccharide purified with Sevay method and the polysaccharide content in crude polysaccharide were significantly different;the method is practical;SPS has anti-tumor effect and can improve immunity.

Key concepts: Polysaccharide, Spleen, In vivo, Phenol, Chemistry, Immunity, Immune system, Traditional medicine

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