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2012•Jiangsu Medical JournalRequires access

Analysis of clinical distribution and drug resistance of Klebsiella pneumoniae

Xiaoping Xue

Open publisher page 1 citations

Abstract

Objective To analyze the clinical distribution and drug resistance of Klebsiella pneumoniae.Methods Data of Klebsiella pneumoniae isolated from clinical specimens from January 2008 to April 2011 were retrospectively analyzed.Results A total of 2536 cases of Klebsiella pneumoniae was isolated,of which the highest rate of drug resistance was to ampicillin(98.62%).Klebsiella pneumoniae remained to be highly sensitive to meropenem,cefoperazone/sulbactam and imipenem,but the drug-resistant strains emerged.The detection rate of extended-spectrum β-lactamases(ESBLs) was 34.98%.Conclusion The timely analysis of bacteria drug-sensitivity is important to guide clinical treatment in this region.

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What this paper is about

Objective To analyze the clinical distribution and drug resistance of Klebsiella pneumoniae.Methods Data of Klebsiella pneumoniae isolated from clinical specimens from January 2008 to April 2011 were retrospectively analyzed.Results A total of 2536 cases of Klebsiella pneumoniae was isolated,of which the highest rate of drug resistance was to ampicillin(98.62%).Klebsiella pneumoniae remained to be highly sensitive to meropenem,cefoperazone/sulbactam and imipenem,but the drug-resistant strains emerged.The detection rate of extended-spectrum β-lactamases(ESBLs) was 34.98%.Conclusion The timely analysis of bacteria drug-sensitivity is important to guide clinical treatment in this region.

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Available abstract

Objective To analyze the clinical distribution and drug resistance of Klebsiella pneumoniae.Methods Data of Klebsiella pneumoniae isolated from clinical specimens from January 2008 to April 2011 were retrospectively analyzed.Results A total of 2536 cases of Klebsiella pneumoniae was isolated,of which the highest rate of drug resistance was to ampicillin(98.62%).Klebsiella pneumoniae remained to be highly sensitive to meropenem,cefoperazone/sulbactam and imipenem,but the drug-resistant strains emerged.The detection rate of extended-spectrum β-lactamases(ESBLs) was 34.98%.Conclusion The timely analysis of bacteria drug-sensitivity is important to guide clinical treatment in this region.

Key concepts: Klebsiella pneumoniae, Sulbactam, Meropenem, Cefoperazone, Imipenem, Drug resistance, Medicine, Microbiology

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