2010•Qilu Pharmaceutical AffairsRequires access

Optimization of extraction conditions of Liubaibaibi Cataplasm by orthogonal

Wenting Yang

Abstract

OBJECTIVE To optimize the extraction process of Liubaibaibi Cataplasm.METHODS Using the orthogonal design,the content of glycyrrhizic acid was determined by HPLC to optimize the extraction process,The investigation factors were ethanol concentration,alcohol volume,extraction time and extract times.RESULTS Extraction of factors in decreasing order of extract timesalcohol volumeextraction timeethanol concentration;extract times was the most Important factor.CONCLUSION The best extraction process of Liubaibaibi Cataplasm was obtained as following:5 times of 50% alcohol,extraction for 3 times and 40min for each time.

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Key concepts: Extraction (chemistry), Chromatography, Chemistry, Alcohol, High-performance liquid chromatography, Process (computing), Computer science, Organic chemistry