Distribution and antibiotic resistance of 3432 clinic isolated pathogenic bacteria

Objective To investigate the distribution and antibiotic resistance of clinic isolated pathogenic bacteria from May 1,2010 to April 30,2011,and instruct the clinic to use drug reasonably.Methods The author Made the identification and antimicrobial susceptibility test of pathogenic bacteria by VITEK 32,analyzed the data with LIS system.Results A total of 3 432 clinical isolates(except fungi)were collected in the whole year,of which Gram-negative bacilli and Gram-positive cocci accounted for 73.6% and 26.4%.The dominant bacteria were Pseudomonas aeruginosa 23.5%(805),Escherichia coli 17.8%(610),Acinetobacter baumannii 11.7%(410),Staphylococcus aureus 9.6%(330),Klebsiella pneumoniae 7.9%(272).The detection rate of extended-spectrum beta-lactamases(ESBLs) to E.coli,Klebsiella pneumoniae were 48% and 24%.Methicillin resistant strains in S.aureus(MRSA) and coagulase negative Staphylococcus(MRCNS) accounted for 83.3% and 77.8% respectively.The resistant rate of Enterococcus to vancomycin was high(21.5%).Conclusion The antibiotic resistance of pathogenic bacteria was severely,it is essential to enhance the drug resistant surveillance so as to guide resonable clinical medicine.