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2006•Acta Academiae Medicinae JiangxiRequires access

Expression of PCNA in Pituitary Adenoma and Its Relation to Tumor Recurrency

Yiyun Li

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Abstract

Objective To investigate the expression of PCNA in human pituitary adenomas and its relation to tumor invasivenes,proliferation and recurrency.Methods Immunohistochemical techniques were used to detect the expression of PCNA in cases of invasive,non-invasive and recurrent pituitary adenomas.Results The expression of PCNA increased significantly in invasive pituitary adenomas group than that in non-invasive group and again the expression of recurrent group increased significantly than that in non-recurrent group.Conclusion The expression of PCNA correlates closely with the invasiveness,proliferation and recurrency in patients with pituitary adenomas.

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Objective To investigate the expression of PCNA in human pituitary adenomas and its relation to tumor invasivenes,proliferation and recurrency.Methods Immunohistochemical techniques were used to detect the expression of PCNA in cases of invasive,non-invasive and recurrent pituitary adenomas.Results The expression of PCNA increased significantly in invasive pituitary adenomas group than that in non-invasive group and again the expression of recurrent group increased significantly than that in non-recurrent group.Conclusion The expression of PCNA correlates closely with the invasiveness,proliferation and recurrency in patients with pituitary adenomas.

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Available abstract

Objective To investigate the expression of PCNA in human pituitary adenomas and its relation to tumor invasivenes,proliferation and recurrency.Methods Immunohistochemical techniques were used to detect the expression of PCNA in cases of invasive,non-invasive and recurrent pituitary adenomas.Results The expression of PCNA increased significantly in invasive pituitary adenomas group than that in non-invasive group and again the expression of recurrent group increased significantly than that in non-recurrent group.Conclusion The expression of PCNA correlates closely with the invasiveness,proliferation and recurrency in patients with pituitary adenomas.

Key concepts: Proliferating cell nuclear antigen, Immunohistochemistry, Pituitary adenoma, Adenoma, Pathology, Pituitary tumors, Medicine, Cancer research

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