Percutaneous renal biopsy in the diagnosis and treatment of acute renal failure

Objective To explore pathological types and causes of acute renal failure(ARF) and evaluate the importance of renal biopsy in the diagnosis and treatment of kidney disease.Methods Thirty cases of ARF with indications for renal biopsy undergone percutaneous renal biopsy through B-ultrasonic-positioning,and analysis was done according to their light microscopy,immune pathology and clinical characteristics.Results Thirty patients with ARF undergone renal biopsy and glomerulus was successfully obtained,with a pass rate of 97%.Pathological analysis showed: 2 patients with sclerosing glomerulonephritis(6.67%),17 patients with primary glomerulonephritis(56.67%),8 patients with secondary glomerulonephritis(26.62%),2 patients with acute tubular necrosis(6.67%) and 1 patient with acute interstitialnephritis(3.33%).In 17 cases of primary glomerulonephritis,there were 3 cases of IgA nephropathy,5 cases of minor glomerular lesions,2 cases of membranous nephropathy,2 cases of focal segmental sclerosing glomerulonephritis,2 cases of capillary proliferative glomerulonephritis and 3 cases of crescentic glomerulonephritis.For secondary glomerulonephritis,there were 6 cases of lupus nephritis and 2 cases of allergic purpura nephritis.Complications occurred in 2 cases of gross hematuria and 1 case of perirenal hematoma.There was no complication such as penetration through other organs by mistake,infection or severe bleeding.Conclusion For patients with acute renal failure,renal biopsy examination plays an extremely important role in identifying the etiology and pathological types,guiding the treatment and defining the prognosis.