2002Journal of Yueyang Normal UniversityRequires access

Preparation of 2,6-O-di-pentyl-3-O-acety1-β-Cyclodextrin and used in Chromatography Separation of Enantiomers

Jianmin Yi

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Abstract

A new alkylated and acetylated β-cyclodextrin has been synthesized and used as chiral stationary phase of gas chromatography,a fused silica capillary column was prepared with this derivative.The performance of the column was investigated and a series of enantiomers were separated.The experimental results indicate that chiral stationary phase is of excellent chromatographic properties and strong enantioselectivity.

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A new alkylated and acetylated β-cyclodextrin has been synthesized and used as chiral stationary phase of gas chromatography,a fused silica capillary column was prepared with this derivative.The performance of the column was investigated and a series of enantiomers were separated.The experimental results indicate that chiral stationary phase is of excellent chromatographic properties and strong enantioselectivity.

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Available abstract

A new alkylated and acetylated β-cyclodextrin has been synthesized and used as chiral stationary phase of gas chromatography,a fused silica capillary column was prepared with this derivative.The performance of the column was investigated and a series of enantiomers were separated.The experimental results indicate that chiral stationary phase is of excellent chromatographic properties and strong enantioselectivity.

Key concepts: Enantiomer, Chromatography, Cyclodextrin, Chemistry, Chiral column chromatography, Derivative (finance), Column chromatography, High-performance liquid chromatography

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Preparation of 2,6-O-di-pentyl-3-O-acety1-β-Cyclodextrin and used in Chromatography Separation of Enantiomers — Research Paper | ScholarLens