ScholarLens Back to search
2002•Harbin Yike Daxue xuebaoRequires access

Effect of taurine on the anti-lipid peroxidation ability of rabbit with ischemia-reperfusion injury

Chun Yang

Open publisher page 0 citations

Abstract

Objective To study the effect of taurine on the ability of anti lipid peroxidation of rabbit with IRI(ischemia reperfusion injury).Methods The rabbits were randomly divided into control group and taurine injection group.Hemorrhagic shock model was created according to improved Wigger's method.The content of SOD and MDA in blood serum was measured before hemorrhagic shock,2h after that and 0.5,1,2h after reperfusion respectively. Results The SOD level of taurine group was higher than that of control group at 0.5h and 1h after reperfusion.The MDA level of taurine group was lower than control group at all periods of time after reperfusion.Conclusion Taurine has anti ISR effect and can restrain lipid peroxidation. The effect is related to the rise of endogenetic SOD activity.

About this research paper

What this paper is about

Objective To study the effect of taurine on the ability of anti lipid peroxidation of rabbit with IRI(ischemia reperfusion injury).Methods The rabbits were randomly divided into control group and taurine injection group.Hemorrhagic shock model was created according to improved Wigger's method.The content of SOD and MDA in blood serum was measured before hemorrhagic shock,2h after that and 0.5,1,2h after reperfusion respectively. Results The SOD level of taurine group was higher than that of control group at 0.5h and 1h after reperfusion.The MDA level of taurine group was lower than control group at all periods of time after reperfusion.Conclusion Taurine has anti ISR effect and can restrain lipid peroxidation. The effect is related to the rise of endogenetic SOD activity.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To study the effect of taurine on the ability of anti lipid peroxidation of rabbit with IRI(ischemia reperfusion injury).Methods The rabbits were randomly divided into control group and taurine injection group.Hemorrhagic shock model was created according to improved Wigger's method.The content of SOD and MDA in blood serum was measured before hemorrhagic shock,2h after that and 0.5,1,2h after reperfusion respectively. Results The SOD level of taurine group was higher than that of control group at 0.5h and 1h after reperfusion.The MDA level of taurine group was lower than control group at all periods of time after reperfusion.Conclusion Taurine has anti ISR effect and can restrain lipid peroxidation. The effect is related to the rise of endogenetic SOD activity.

Key concepts: Taurine, Lipid peroxidation, Reperfusion injury, Malondialdehyde, Shock (circulatory), Chemistry, Hemorrhagic shock, Ischemia

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Effect of taurine on the anti-lipid peroxidation ability of rabbit with ischemia-reperfusion injury — Research Paper | ScholarLens