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Clinical Study on Effects of Ischemic Preconditioning in Patients with Acute Myocardial Infarction

Ren Feng-xue

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Abstract

Objective:To investigate the short-term effects of ischemic preconditioning(IP) on left ventricular function and infarction size in patients with acute myocardial infarction. Methods:109 patients with first acute myocardial infarction: divided into group IP and group without IP.The effects of IP on peak creatine kinase value and left ventricular function were analyzed separately. Results:(1)The peak creatine kinase value and the peak creatine kinase MB fractions were significantly lower in group IP than group IP(P0.01),at the time,the left ventricular ejection fraction(LVEF) and ratio of the early peak velocity /the late peak velocity in diastole of mitral flow(E/A) were significantly higher in group A than group B(P0.05) Conclusions:IP could limit infarct size,protect the left ventricular function in patients with acute myocardial infarction.

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What this paper is about

Objective:To investigate the short-term effects of ischemic preconditioning(IP) on left ventricular function and infarction size in patients with acute myocardial infarction. Methods:109 patients with first acute myocardial infarction: divided into group IP and group without IP.The effects of IP on peak creatine kinase value and left ventricular function were analyzed separately. Results:(1)The peak creatine kinase value and the peak creatine kinase MB fractions were significantly lower in group IP than group IP(P0.01),at the time,the left ventricular ejection fraction(LVEF) and ratio of the early peak velocity /the late peak velocity in diastole of mitral flow(E/A) were significantly higher in group A than group B(P0.05) Conclusions:IP could limit infarct size,protect the left ventricular function in patients with acute myocardial infarction.

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Available abstract

Objective:To investigate the short-term effects of ischemic preconditioning(IP) on left ventricular function and infarction size in patients with acute myocardial infarction. Methods:109 patients with first acute myocardial infarction: divided into group IP and group without IP.The effects of IP on peak creatine kinase value and left ventricular function were analyzed separately. Results:(1)The peak creatine kinase value and the peak creatine kinase MB fractions were significantly lower in group IP than group IP(P0.01),at the time,the left ventricular ejection fraction(LVEF) and ratio of the early peak velocity /the late peak velocity in diastole of mitral flow(E/A) were significantly higher in group A than group B(P0.05) Conclusions:IP could limit infarct size,protect the left ventricular function in patients with acute myocardial infarction.

Key concepts: Medicine, Myocardial infarction, Cardiology, Internal medicine, Ejection fraction, Creatine kinase, Infarction, Ischemic preconditioning

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