Analysis of the clinical efficacy and safety of trajenta combined with acarbose in the treatment of senile diabetes

Objective:To investigate the clinical efficacy and the adverse reaction of trajenta combined with acarbose in the treatment of senile diabetes mellitus(type 2).Methods:50patients with senile type 2diabetes in our hospital were randomized into the observation group and the control group with 25 cases each.The control group were treated with acarbose,while the observation group were with trajenta combined with acarbose.After 4months' treatment,the clinical efficacy and adverse reaction between both groups were compared.Results:Compared with patients before the treatment,FPG,2hPG and HbAlc in both groups were significantly decreased after the treatment,which were of statistical differences(P0.05);compared with the control group,FPG,2hPG,and HbAlc in the observation group decreased more significantly,which was of statistical differnce(P0.05);as for the adverse effect,there was no difference between both groups(P0.05);and after the treatment,there was no statistical difference of BMI between both groups(P0.05).Conclusion:Compared with the acarbose treatment,trajenta combined with acarbose are more effective in improving FPG,2hPG and HbAlc of patients with type 2diabetes.Moreover,they are safer and will not lead to gaining weight and hypoglycemia of patients.