CORRELATION BETWEEN SERUM LEVEL OF PROCALCITONIN AND APACHE II SCORE IN PATIENTS WITH SEPSIS

Objective To study the correlation of serum level of procalcitonin(PCT) with score of APACHE Ⅱ in patients with sepsis.Methods Serum levels of PCT and C-reactive protein(CRP) in 74 patients with sepsis,which included sepsis(28 cases),severe sepsis(25) and septic shock(21),and 24 patients with non-sepsis were detected.APACHE Ⅱscore was done.The correlation of the score with PCT and C-reactive protein(CRP) was analyzed.Results Serum levels of PCT and CRP,and APACHEⅡ scores in patients with sepsis,severe sepsis and septic shock were significantly higher than that in the non-septic patients(F=7.07-441.87,q=3.18-48.14,P0.05).PCT levels and APACHEⅡ scores elevated along with the severity of the disease(q=10.06-48.14,P0.05).The level of PCT was positively correlated with APACHEⅡ(r=0.68,P0.05).Conclusion There is a positive correlation of PCT with APACHE Ⅱ score in patients with sepsis.The serum level of PCT is superior to CRP in the diagnosis of sepsis