Diagnostic and Prognosis-Evaluted Value of Serum Procal Citonin and C-Reactive Protein on Sepsis

Objective To explore the diagnostic and prognosis-evaluted value of serum procal citonin( PCT) and Creactive protein( CRP) on sepsis. Methods A total of 120 patients in our hospital EICU from July 2012 to May 2013,including 63 cases of sepsis( sepsis group) and 57 cases of cases of non-sepsis( non-sepsis group) were tested the levels of serum PCT and CRP. Sepsis patients were divided into survival group and death group according the prognosis. Results The levels of serum PCT and CRP,as well as acute physiology and chronic health evaluation Ⅱ( APACHEⅡ) scores and sepsis related organ failure assessment( SOFA) scores in the sepsis group were significantly larger than those in the nonsepsis and control groups( P 0. 05). The sensitivity,specificity,positive predictive value,and negative predictive value for serum PCT in diagnosing sepsis were significantly larger than those for serum CRP( P 0. 05). The levels of serum PCT and CRP in survival group were less than those in death group on the 1,3,5,and 7 days( P 0. 05). Moreover,there was significant time effects on level of serum PCT1 and CRP in survival group( P 0. 05),but not in death group( P 0. 05).Conclusions The levels of serum PCT and CRP are reliability indexes for in diagnosing sepsis and evaluating prognosis. Moreover the sensitivity and specificity of serum PCT were better those of serum CRP