Optimum of extraction process for crude drugs in Baibixiao qintment by combined multiple factors experiment analysis
Jingping Chen
Abstract
Jingping Chen
Abstract
OBJECTIVE To optimize the extraction process of the crude medicine in Baibixiao qintment.METHODS By the emodin,the chrsophanol rhubarb content determination and psoriasis mouse model experiment were combined,L9(34) orthogonal testing method was used to its essential step like watering quantity,the decoction time,the decoction times conditions for adding alcohol.RESULTS The influence factors were listed as BDAC and BDCA.Factor B(decoction times) had the significance influence(P0.05).CONCLUSION The optimum process of water volume 8 times of herbal weight was selected the extraction was conducted three time,1.5 h each time.
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OBJECTIVE To optimize the extraction process of the crude medicine in Baibixiao qintment.METHODS By the emodin,the chrsophanol rhubarb content determination and psoriasis mouse model experiment were combined,L9(34) orthogonal testing method was used to its essential step like watering quantity,the decoction time,the decoction times conditions for adding alcohol.RESULTS The influence factors were listed as BDAC and BDCA.Factor B(decoction times) had the significance influence(P0.05).CONCLUSION The optimum process of water volume 8 times of herbal weight was selected the extraction was conducted three time,1.5 h each time.
Key concepts: Decoction, Emodin, Extraction (chemistry), Crude drug, Chromatography, Traditional medicine, Process (computing), Chemistry