Impacts of Systemic Imflammatory Response Syndrome on the Prognosis of Patients with Acute Pancreatitis

Objective:To investigate impacts of Systemic Inflammatory Response Syndrome (SIRS)on the prognosis of patients with acute pancreatitis.Methods:280 patients with acute pancreatitis between 1997 and 2000 were divided into non SIRS and SIRS groups.Furthermore,SIRS group was categorized into three subgroups according to the numbers of SIRS criteria and two subgroups with infection or without infection.The prognosis was evaluated by mortality.Results:Morbidity of SIRS in this group was 48.6%.Mortality of SIRS group(8.09%) was significantly higher than that of non SIRS group(1.39%), morbidity of SIRS(81.8%)and mortality(30.3%)of patients with acute severe pancreatitis were remarkably higher than those of simple ones(44.1% and 1.21%,respectively).Mortalities of group with infection were higher than that of group without infection.Conclusions:There is a close relation between prognosis and morbidity of SIRS and occurrence of infection in patients with acute pancreatitis.