The curative effect and influence factor of myelomeningocel microsurgery treatment(report of 532 cases)

Objective To discuss therapeutic effect of microsurgery treatment of myelomeningocel by analyzing the clinical data of 532 cases. Methods Examinations in nervous system and MRI were conducted. The microsurgical treatment of myelomeningocel was performed in all cases and the therapeutic effectiveness after operation was graded according to the physical improvement of the patients: excellent, effective, ineffective and aggravation. Results The degree of untethering at microsurgery which was based on Kirollos grading system was assessed: GradeⅠin 519 cases (97.6%), GradeⅡ in 11 cases (2.0%), GradeⅢin 2cases (0.4%). Recent curative effectiveness in 532 patients was recorded, among them 81 cases(15.2%) excellent, 321 cases(60.3%) effective,125 cases(23.5%) not changed and 5 case(0.93%) aggravated. Conclusions The early standard surgery may avoid the patients’ serious disability. By clinical practice of MRI、dynamics as well as the neuroelectricity physiology, microsurgery may enhance curative effect of myelomeningocel greatly.