Clinical observation on urokinase thrombolysis in treatment of acute myocardial infarction

Objective To observe the curative effect and experience on urokinase thrombolysis in treatment of acute myocardial infarction.Methods The clinical materials of 160 patients with acute myocardial infarction were reviewed and analyzed from Jan 2010 to Jun 2012.Results Compared with the non-thrombolysis group,the recanalization rate of coronary artery in the other group was significantly higher,and the death rate was significantly lower.But there was no significant difference by untoward reaction between them.By the thrombolytic therapy,the thrombolytic starting time in the thrombolysis group was(4.2±0.9) h while the other group was(7.5 ±0.6) h.With the thrombolytic starting time prolonged,the recanalization rate was decreased gradually,and the death rate was increased gradually.Compared with the non-recanalization group,the rate of arrhythmia in the recanalization group was significantly higher(P 0.05).Conclusion For the treatment of acute myocardial infarction,the urokinase thrombolysis should be carried out early.It can improve the recanalization rate,prognosis of patients and the quality of life.