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2004•Chinese Journal of Laboratory DiagnosisRequires access

Expression of ER,PR and C-erbB-2 in breast cancer and their significance

Yang De

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Abstract

Objective To reveal the expression of ER, PR and c|erbB|2 gene protein in breast cancer and their clinical significance. Methods using Immunohistochemical technique,detect the expression of ER, PR and c|erbB|2 in 164 cases of breast cancer. Results ER and PRnegatively correlated with clinical TNM stages, but c|erbB|2 positively correlated with them.Conclusion For breast cancer, the positive expression of c|erbB|2 might serve as indixators for poor prognosis, but ER and PR positive expression were indicators for well prognosis.

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Objective To reveal the expression of ER, PR and c|erbB|2 gene protein in breast cancer and their clinical significance. Methods using Immunohistochemical technique,detect the expression of ER, PR and c|erbB|2 in 164 cases of breast cancer. Results ER and PRnegatively correlated with clinical TNM stages, but c|erbB|2 positively correlated with them.Conclusion For breast cancer, the positive expression of c|erbB|2 might serve as indixators for poor prognosis, but ER and PR positive expression were indicators for well prognosis.

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Available abstract

Objective To reveal the expression of ER, PR and c|erbB|2 gene protein in breast cancer and their clinical significance. Methods using Immunohistochemical technique,detect the expression of ER, PR and c|erbB|2 in 164 cases of breast cancer. Results ER and PRnegatively correlated with clinical TNM stages, but c|erbB|2 positively correlated with them.Conclusion For breast cancer, the positive expression of c|erbB|2 might serve as indixators for poor prognosis, but ER and PR positive expression were indicators for well prognosis.

Key concepts: Breast cancer, Immunohistochemistry, Clinical significance, Medicine, Oncology, Internal medicine, Cancer, Cancer research

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Expression of ER,PR and C-erbB-2 in breast cancer and their significance — Research Paper | ScholarLens