Curative Effect Study on Acitretin A combined with compound glycyrrhizin in treating 60 cases of psoriasis vulgaris

[Objective]To observe the curative effect of Acitretin A combined with compound glycyrrhizin in treating 60 cases of psoriasis vulgaris,and provide basis for clinical treatment.[Methods]Totally 120 cases of psoriasis vulgaris were randomly divided into treatment group and control group,with 60 cases in each group. The control group adopted oral Acitretin A therapy,and the treatment group added compound glycyrrhizin on the basis of the control group,lasting 8-12 weeks. [Results]PASI score in the treatment group after treatment was much lower than the control group( P 0. 01). The total effective rate of the treatment group was 93. 3%,much higher than the control group( 75. 0%,P 0. 01). Both of the groups existed adverse effect in different extent, but there was no significant difference between the 2 groups( P 0. 05). [Conclusion]Acitretin A combined with compound glycyrrhizin can raise curative effect,reduce side effect of liver and kidney and adverse effect in treating psoriasis vulgaris. It is a kind of safe and high-performance treatment method.