Relevance of dynamic changes of PCT and CRP with MODS after severe multiple trauma

Objective To investigate the relation of the peripheral blood procalcitonin(PCT),C-reactive protein(CRP)and multiple organ dysfunction syndrome(MODS) for patients with multiple trauma.Methods A total of 76 patients with multiple trauma were divided into non-MODS group and MODS group.Peripheral blood PCT and CRP concentration were detected.Results The PCT and CRP level of the control group changed a little during the whole observation.The highest concentration of PCT value in the two groups was observed on the first day after injury,and then declined gradually.Peripheral blood concentration of CRP in non-MODS group had a downward trend.The highest concentration of peripheral blood CRP appeared on the second day after injury and then declined in MODS group.CRP concentrations were significantly different compared with that in the control group.By taking CRP as an indicator of the diagnosis of MODS,CRP was more efficient than PCT.Conclusion The results suggest that the CRP level is relevant to the occurence of secondary MODS after trauma.The observation of peripheral serum CRP concentration can predict the occurrence of secondary MODS.