Chemical constituents of Memorialis hirta
Jing Huang
Abstract
Jing Huang
Abstract
AIM To study the chemical constituents of Memorialis hirta.METHODS The powdered whole herb of Memorialis hirta was extracted by 95% ethanol,and the extract was suspended in water and partitioned with petroleum ether,EtOAc,and n-butanol.The extract from EtOAc part was isolated and purified by silica gel column chromatography and recrystallization means,and all compounds were identified by the means of spectroscopic analysis and physico-chemical property.RESULTS Twelve compounds were obtained and all the compounds were elucidated as friedelin(1),epifriedelanol(2),β-amyin(3),α-amyin(4),lupeol(5),β-sitosterol(6),stigmasterol(7),oleanolic acid(8),ursolic acid(9),pomalic acid(10),β-sitosterol 3-O-β-D-glucopyranoside(11),and stigmasterol 3-O-β-D-glucopyranoside(12),respectively.CONCLUSION All compounds are obtained from the genus Memorialis for the first time.
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AIM To study the chemical constituents of Memorialis hirta.METHODS The powdered whole herb of Memorialis hirta was extracted by 95% ethanol,and the extract was suspended in water and partitioned with petroleum ether,EtOAc,and n-butanol.The extract from EtOAc part was isolated and purified by silica gel column chromatography and recrystallization means,and all compounds were identified by the means of spectroscopic analysis and physico-chemical property.RESULTS Twelve compounds were obtained and all the compounds were elucidated as friedelin(1),epifriedelanol(2),β-amyin(3),α-amyin(4),lupeol(5),β-sitosterol(6),stigmasterol(7),oleanolic acid(8),ursolic acid(9),pomalic acid(10),β-sitosterol 3-O-β-D-glucopyranoside(11),and stigmasterol 3-O-β-D-glucopyranoside(12),respectively.CONCLUSION All compounds are obtained from the genus Memorialis for the first time.
Key concepts: Stigmasterol, Friedelin, Lupeol, Chemistry, Petroleum ether, Chromatography, Oleanolic acid, Recrystallization (geology)