ScholarLens Back to search
2013•Journal of environmental healthRequires access

Determination of 11 sulfonamides residues in soil by ultra performance liquid chromatography-tandem mass spectrometry

Gan Ping-shen

Open publisher page 0 citations

Abstract

Objective To develop a fast ultra liquid chromatography-tandem mass spectrometric(UPLC-MS/MS) method for determination of 11 sulfonamides residues in soil.Methods The samples were extracted with pH 4.0 citric acid solutionaeetonitrile(V∶V=1∶1) containing 0.1 mol/L EDTA and purified by SAX and HLB SPE column.The analytes were separated by ultra C18 column and UPLC-MS/MS analysis was performed on multiple reaction monitoring mode under positive ion electrospray ionization with the external method.Results The average recoveries at 2.5,10 and 50 μg/kg were 69.6%-98.5% and the relative standard deviations ranged from 5.9%-15.2%.The linearity was satisfactory with a correlation coefficient of 0.998 8 at 2-200 μg/L.The limit of quantization was 0.23-1.64 μg/kg.Conclusion This method is fast and applicable to the quantitative analysis of sulfonamides residues in soil.

About this research paper

What this paper is about

Objective To develop a fast ultra liquid chromatography-tandem mass spectrometric(UPLC-MS/MS) method for determination of 11 sulfonamides residues in soil.Methods The samples were extracted with pH 4.0 citric acid solutionaeetonitrile(V∶V=1∶1) containing 0.1 mol/L EDTA and purified by SAX and HLB SPE column.The analytes were separated by ultra C18 column and UPLC-MS/MS analysis was performed on multiple reaction monitoring mode under positive ion electrospray ionization with the external method.Results The average recoveries at 2.5,10 and 50 μg/kg were 69.6%-98.5% and the relative standard deviations ranged from 5.9%-15.2%.The linearity was satisfactory with a correlation coefficient of 0.998 8 at 2-200 μg/L.The limit of quantization was 0.23-1.64 μg/kg.Conclusion This method is fast and applicable to the quantitative analysis of sulfonamides residues in soil.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To develop a fast ultra liquid chromatography-tandem mass spectrometric(UPLC-MS/MS) method for determination of 11 sulfonamides residues in soil.Methods The samples were extracted with pH 4.0 citric acid solutionaeetonitrile(V∶V=1∶1) containing 0.1 mol/L EDTA and purified by SAX and HLB SPE column.The analytes were separated by ultra C18 column and UPLC-MS/MS analysis was performed on multiple reaction monitoring mode under positive ion electrospray ionization with the external method.Results The average recoveries at 2.5,10 and 50 μg/kg were 69.6%-98.5% and the relative standard deviations ranged from 5.9%-15.2%.The linearity was satisfactory with a correlation coefficient of 0.998 8 at 2-200 μg/L.The limit of quantization was 0.23-1.64 μg/kg.Conclusion This method is fast and applicable to the quantitative analysis of sulfonamides residues in soil.

Key concepts: Chemistry, Chromatography, Mass spectrometry, Detection limit, Analyte, Electrospray ionization, Tandem mass spectrometry, Selected reaction monitoring

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Determination of 11 sulfonamides residues in soil by ultra performance liquid chromatography-tandem mass spectrometry — Research Paper | ScholarLens