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2007•Qilu Pharmaceutical AffairsRequires access

Determination of Paeonol in Jingdaining capsules by HPLC

LU Xiao-qun

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Abstract

OBJECTIVE To determine the content of Paeonol by RP-HPLC in Jingdaining Capsules.METHODS The HPLC system consisted of Kromasil C18 column(150mm×4.6mm,5μm).The flow rate was 1ml·min-1 and the detective wavelength was 274nm.RESULTS The calibration curve was linear in the range of 12.72～127.20μg·ml-1 for Paeonol.The average recovery was 99.26%.RSD=1.2%(n=6).CONCLUSION The HPLC method is simple,reliable,specific,and can be used for the quality control of Jingdaining capsules.

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OBJECTIVE To determine the content of Paeonol by RP-HPLC in Jingdaining Capsules.METHODS The HPLC system consisted of Kromasil C18 column(150mm×4.6mm,5μm).The flow rate was 1ml·min-1 and the detective wavelength was 274nm.RESULTS The calibration curve was linear in the range of 12.72～127.20μg·ml-1 for Paeonol.The average recovery was 99.26%.RSD=1.2%(n=6).CONCLUSION The HPLC method is simple,reliable,specific,and can be used for the quality control of Jingdaining capsules.

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Available abstract

OBJECTIVE To determine the content of Paeonol by RP-HPLC in Jingdaining Capsules.METHODS The HPLC system consisted of Kromasil C18 column(150mm×4.6mm,5μm).The flow rate was 1ml·min-1 and the detective wavelength was 274nm.RESULTS The calibration curve was linear in the range of 12.72～127.20μg·ml-1 for Paeonol.The average recovery was 99.26%.RSD=1.2%(n=6).CONCLUSION The HPLC method is simple,reliable,specific,and can be used for the quality control of Jingdaining capsules.

Key concepts: Paeonol, Chromatography, High-performance liquid chromatography, Calibration curve, Chemistry, Medicine, Detection limit, Pathology

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