The Application Values Of Detection of SCC and CA125 In Squamous Cell Carcinoma of the Cervix

Objective To study the clinical value of squamous cell carcinoma associated antigen(SCC) and CA125 in the diagnosis and monitoring of squamous cell carcinoma of the cervix.Methods The samples of peripheral venous blood from 85 patients with cervix squamouscell carcinoma,60 patients with cervical intraepithelial neoplasia(CIN) and 45 healthy women were collected.Then the serum SCC was measured by IMX,and CA125 was measured by Roche E170.Results The levels and positive rates of SCC were significantly higher than those in the other groups(P0.05),but the levels and positive rates of CA125 were not variable.With the increasing of FIGO stage,the levels and positive rates of SCC and the levels of CA125 increased significantly(P0.05).The post-treatment SCC level was significantly lower than that of pretreatment(P0.05).But CA125 level was not variable.Both SCC and CA125 did not change with the pathological grades significantly.Conclusion SCC contributes to the diagnosis of cervix squamous cell carcinoma and observing therapeutic efficacy.CA125 is not so helpful for cervix squamous cell carcinoma in the diagnosis and observing therapeutic efficacy.The combined determination can improve the diagnostic sensitivity.