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2008•The Journal of Medical Theory and PracticeRequires access

The Application of Chemilumioometry in Measurement of Serum Fibrosis Indexes for the Diagnosis of Hepatic Fibrosis

Fang Liu

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Abstract

Objective:To assess the practical value of chemiluminometry in measuring serum fibrosis index for the diagnosis of hepatic fibrosis.Methods:76 serum samples from patients with chronic hepatitis B were examined for measuring fibrosis indexes using chemiluminometry technique,and liver biopsy was performed.Results: The levels of HA,PIIIP and Ⅳ.C were increased and correlated positively with stage of fibrosis(r=0.693,P0.01;r=0.753,P0.01;r=0.742,P0.01).Conclusion:Serum fibrosis indexes can help predict the tendency of hepatic fibrosis,and the method produces results with the advantages of high sensitivity,high stability,cross-contamination-proof,and promptness.

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What this paper is about

Objective:To assess the practical value of chemiluminometry in measuring serum fibrosis index for the diagnosis of hepatic fibrosis.Methods:76 serum samples from patients with chronic hepatitis B were examined for measuring fibrosis indexes using chemiluminometry technique,and liver biopsy was performed.Results: The levels of HA,PIIIP and Ⅳ.C were increased and correlated positively with stage of fibrosis(r=0.693,P0.01;r=0.753,P0.01;r=0.742,P0.01).Conclusion:Serum fibrosis indexes can help predict the tendency of hepatic fibrosis,and the method produces results with the advantages of high sensitivity,high stability,cross-contamination-proof,and promptness.

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Available abstract

Objective:To assess the practical value of chemiluminometry in measuring serum fibrosis index for the diagnosis of hepatic fibrosis.Methods:76 serum samples from patients with chronic hepatitis B were examined for measuring fibrosis indexes using chemiluminometry technique,and liver biopsy was performed.Results: The levels of HA,PIIIP and Ⅳ.C were increased and correlated positively with stage of fibrosis(r=0.693,P0.01;r=0.753,P0.01;r=0.742,P0.01).Conclusion:Serum fibrosis indexes can help predict the tendency of hepatic fibrosis,and the method produces results with the advantages of high sensitivity,high stability,cross-contamination-proof,and promptness.

Key concepts: Medicine, Fibrosis, Hepatic fibrosis, Chronic hepatitis, Gastroenterology, Internal medicine, Liver biopsy, Liver fibrosis

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