Progress of Research on MicroRNA and tumor

MicroRNA discovered recently is a class of non-coding single-stranded RNA molecules associated with the regulation of gene expression.It is length of about 21-22 base pairs,and can cause inhibition of target mRNA degradation or translation by specific binding of the target mRNA base pairs,furtherly regulated gene expression of post-transcription.MicroRNA can regulate cell's differentiated,proliferation,apoptosis,metabolism by interfering with gene expression.Abnormal expression of microRNA can cause disorder of cell's differentiated,proliferation,apoptosis,metabolism,which is closely related to the occurrence and development of tumor.MicroRNA is biological markers of new molecular,which is important potential value in diagnosis and treatment of tumor.