2007•The Journal of Clinical PsychiatryRequires access

A study of quetiapine and risperidone in treatment of chronic schizophrenia

Huo Xu-pin

Abstract

Objective:To compare the efficacy and safety between quetiapine and risperidone in the treatment of chronic schizophrenia.Method:Seventy patients with chronic schizophrenia were randomly divided into two groups receiving quetiapine or risperidone treatment respectively.The period of treatment were 8 weeks.The positive and negative symptom scale(PANSS) and treatment emergent symptom scale(TESS) were used to evaluate the efficacy and side effects.Results:Both groups had similar efficacy and severity of side effects.Conclusion:Both quetiapine and risperidone have definite effect and rather high safety in the treatment of chronic schizophrenia.

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Key concepts: Risperidone, Quetiapine, Schizophrenia (object-oriented programming), Negative symptom, Psychiatry, Medicine, Psychology, Internal medicine