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1999•Chinese Journal of New Drugs and Clinical RemediesRequires access

Etofesalamide ointment in treatment of chronic eczema: A randomized controlled trial

John P. New, Changhai Ding

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Abstract

AIM: To evaluate the efficacy and safety of etofesalamide ointmant in the treatment of chronic eczema. METHODS: A randomized, single_blind and controlled clinical trial of etofesalamide ointment vs its ointment base was performed. Thirty patients (M 23, F 7; age 50 a±s 15 a) with chronic eczema were treated with etofesalamide ointment (given thinly on the surface 3 times daily) for 4 wk; Another 30 patients (M 24, F 6; age 44 a±14 a) were treated with ointment base (given thinly on the surface 3 times daily) for 4 wk. RESULTS: The efficacy rates of etofesalamide ointment and the base on 2 wk and 4 wk were 20%, 63%, and 10%, 14%, respectively. The adverse reaction rates of etofesalamide ointment and the ointment base were 7% and 3%, respectively. CONCLUSION: Etofesalamide ointment is effective in the treatment of chronic eczema with mild adverse reactions.

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What this paper is about

AIM: To evaluate the efficacy and safety of etofesalamide ointmant in the treatment of chronic eczema. METHODS: A randomized, single_blind and controlled clinical trial of etofesalamide ointment vs its ointment base was performed. Thirty patients (M 23, F 7; age 50 a±s 15 a) with chronic eczema were treated with etofesalamide ointment (given thinly on the surface 3 times daily) for 4 wk; Another 30 patients (M 24, F 6; age 44 a±14 a) were treated with ointment base (given thinly on the surface 3 times daily) for 4 wk. RESULTS: The efficacy rates of etofesalamide ointment and the base on 2 wk and 4 wk were 20%, 63%, and 10%, 14%, respectively. The adverse reaction rates of etofesalamide ointment and the ointment base were 7% and 3%, respectively. CONCLUSION: Etofesalamide ointment is effective in the treatment of chronic eczema with mild adverse reactions.

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Available abstract

AIM: To evaluate the efficacy and safety of etofesalamide ointmant in the treatment of chronic eczema. METHODS: A randomized, single_blind and controlled clinical trial of etofesalamide ointment vs its ointment base was performed. Thirty patients (M 23, F 7; age 50 a±s 15 a) with chronic eczema were treated with etofesalamide ointment (given thinly on the surface 3 times daily) for 4 wk; Another 30 patients (M 24, F 6; age 44 a±14 a) were treated with ointment base (given thinly on the surface 3 times daily) for 4 wk. RESULTS: The efficacy rates of etofesalamide ointment and the base on 2 wk and 4 wk were 20%, 63%, and 10%, 14%, respectively. The adverse reaction rates of etofesalamide ointment and the ointment base were 7% and 3%, respectively. CONCLUSION: Etofesalamide ointment is effective in the treatment of chronic eczema with mild adverse reactions.

Key concepts: Medicine, Randomized controlled trial, Adverse effect, Clinical trial, Dermatology, Surgery, Internal medicine

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