2005•China Public HealthRequires access

Protection effect of selenium and organo-germanium-132 on ethanol injury in rats

Mai Huixia

Abstract

Objective To approach protection of selenium and organo-germanium-132 on the rat's tissue injury of alcoholism.Methods Ethanol dependent rats were formed by using 52%,5.0g/(kg·bw)Erguotou(Beijing Hongxing).The rats was ingested for 3 months and the contents of malondialdehyde(MDA),glutathione (GSH) and activity of superoxide dismutase(SOD)in liver,renal,brain and Serum were detected.Results The content of MDA was decreased(P0.01),the contents of GSH and the activities of superoxide dismitase(SOD)were increased in tissue and serum among alcohol+Se,alcohol+Ge-132,alcohol+Se+Ge-132 and alcohol groups(P0.05).Conclusion Selenium and organo-germanium-132 can inhibit the injury of over-dose alcohol to body by elevating contents of GSH,activities of SOD.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Malondialdehyde, Selenium, Alcohol, Chemistry, Superoxide dismutase, Ethanol, Glutathione, Germanium