Efficacy and safety of Repaglinide in treatment of patients with Type 2 Diabetes Mellitus

Objective To evaluate the efficacy and safety of an antidiabetic agent repaglinide in the treatment of type 2 diabetes. Method 126 cases of type 2 diabetes patients were randomly assigned to repaglinide group or glibenclamide group. The whole observation lasted 12 weeks. Result Similar decreases in fasting blood glucose, 2h postprandial blood glucose and HbA1c were showed in both repaglinide and glibenclamide groups. There was a lower incidence of hypoglycemia by repaglinide thanglibenclamide (3. 17% vs14. 29% , P0. 01) . Conclusion Repaglinide is effective and safe in the treatment of new diagnostic type 2 diabetes.