Analysis of brain natriuretic peptide in the diagnosis and prognosis of senile heart failure evaluation

Objective To study the changes of serum BNP in elderly patients with heart failure,and to evaluate BNP in diagnosis and assessment of the value in the clinical application of senile heart failure.Methods Compared different NYHA heart function classification senile heart failure patients' serum BNP,cTn1,MYO laboratory indicators;and Studied the BNP and LVEDD,LVEF correlation.Results BNP in heart failure I group and the control group showed no significant difference(P 0.05),one of the other two groups were statistically different(P 0.05);cTn1,MYO,IV Ⅲ group,heart failure group compared with other groups was statistically significant(P 0.05);179 cases of BNP and LVEDD in elderly patients with heart failure,LVEF by the Spearman correlation analysis,LVEDD was positively correlated with BNP(r = 0.714,P 0.05),LVEF was negatively correlated with BNP(r =-0.639,P 0.05).Conclusion BNP has important clinical value in the early diagnosis of heart failure,worthy of clinical application.