Experimental Study on Safe Retention Time of Intravenous Indwelling Needle

Objective To study on the influence of different retention time of intravenous indwelling needle in rabbits on vscular intima and explore the optimal retention time.Methods Thirty healthy adult New-Zeland rabbits were selected as the study sample and evenly divided into three groups in random.The retention time of indwelling needle in ear marginal vein of rabbits was 3 d,7 d and 9 d in three groups respectively.After specified retention time,all the rabbits were killed and specimen was obtained to be routinely dehydrated,waxed,embedded,sliced,hematoxylin and eosin stained.Then the vascular changes were observed by light microscopy.Results The appearance of vein vessels in three groups was good,without changes of stiffness or trabs.Decreased elasticity was only found in one specimam in the group of 9 d retention of indwelling needle.There was not statistical difference in phlebitis among three groups(P0.05).Conclusion On the basis of strictly following the procedure of practice,we can prolong the retention time of intravenous indwelling needle to 7～9 d if the medication is less irritating.