Clinical analysis of high dose ambroxol in the treatment of patients with radiation pneumonitis

Objective To observe the clinical effect of high dose ambroxol in the treatment of radiation pneumonitis patients. Methods 108 patients were randomly divided into the test group and the control group,54 cases in each group. All patients were given ambroxol on the base of glucocorticoid and antibiotics. The dose of the control group was 60 mg,twice a day,and the dose of the test group was 300 mg,twice a day. One treatment course was2 weeks. The efficacy,signs and symptoms disappear time and Leicester Cough Questionnaire( LCQ) of the two groups were compared. Results The total effective rate of the test group was 96. 3%,which was significantly higher than that of the control group( 81. 5%,P 0. 05). The signs and symptoms disappear time was significantly shorter in the test group than in the control group. The LCQ score was significantly higher in the test group than in the control group. There was no significant difference in the incidence of adverse reactions between the two groups. Conclusion The clinical effect of high dose ambroxol for radiation pneumonitis patients is satisfactory and safe,which can promote the recovery of patients and improve the patient's quality of life and fewer adverse reactions.