2006•The Journal of Clinical PsychiatryRequires access

Comparative study between aripiprazole and clozapine in the treatment of patients with schizophrenia

Zhang Yong-l

Abstract

Objective:To detect the clinical efficacy and side effect of aripiprazole and clozapine in the treatment of first episode schizophrenic patients. Method:64 schizophrenic inpatients have been divided into aripiprazole group and clozapine group randomly to treat for 8 weeks.Positive and negative symptom scale(PANSS) and treatment emergent symptom scale(TESS) were used to evaluate the efficacy and side effects respectively. Results:There were no significant difference in efficacy between two groups.Aripiprazole had less side effects than clozapine. Conclusion:Aripiprazole is a safe and effective antipsychotic drug.

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Key concepts: Aripiprazole, Clozapine, Schizophrenia (object-oriented programming), Antipsychotic drug, Clinical efficacy, Antipsychotic, Psychology, Medicine