Chemical constituents of Paeonia lactiflora Pall.
Hui‐Jun Li
Abstract
Hui‐Jun Li
Abstract
Objective: To study the chemical constituents of Paeonia lactiflora Pall..Methods: Varied column chromatographies were used to isolate chemical constituents from the EtOH extract of Radix Paeoniae Alba.The structures were identified by MS,NMR data.Results: Sixteen compounds were isolated and identified as desbenzoylpaeoniflorin(1),benzoylpaeoniflorin(2),galloylpaeoniflorin(3),paeoniflorin(4),albiflorin(5),gallic acid(6),methyl gallate(7),ethyl gallate(8),(+)-catechin(9),1,2,3,4,6-penta-O-galloyl-D-glucose(10),(2S,3S,4R,8E)-2-[(2′R)-2′-hydroxypentracosanoylamino]-8-octadecene-1,3,4-triol(11),1-O-β-D-glucopyranosyl-(2S,3S,4R,8E)-2-[(2′R)-2′-hydroxypalmitoylamino]-8-octadecene-1,3,4-triol(12),1-O-β-D-glucopyranosyl-(2S,3S,4R,8E)-2-[(2′R)-2′-hydroxytetracosanamino]-8-octadecene-1,3,4-triol(13),benzoic acid(14),β-daucosterol(15),β-sitosterol(16).Conclusion: Compounds 11-13 were isolated from this genus for the first time.
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Objective: To study the chemical constituents of Paeonia lactiflora Pall..Methods: Varied column chromatographies were used to isolate chemical constituents from the EtOH extract of Radix Paeoniae Alba.The structures were identified by MS,NMR data.Results: Sixteen compounds were isolated and identified as desbenzoylpaeoniflorin(1),benzoylpaeoniflorin(2),galloylpaeoniflorin(3),paeoniflorin(4),albiflorin(5),gallic acid(6),methyl gallate(7),ethyl gallate(8),(+)-catechin(9),1,2,3,4,6-penta-O-galloyl-D-glucose(10),(2S,3S,4R,8E)-2-[(2′R)-2′-hydroxypentracosanoylamino]-8-octadecene-1,3,4-triol(11),1-O-β-D-glucopyranosyl-(2S,3S,4R,8E)-2-[(2′R)-2′-hydroxypalmitoylamino]-8-octadecene-1,3,4-triol(12),1-O-β-D-glucopyranosyl-(2S,3S,4R,8E)-2-[(2′R)-2′-hydroxytetracosanamino]-8-octadecene-1,3,4-triol(13),benzoic acid(14),β-daucosterol(15),β-sitosterol(16).Conclusion: Compounds 11-13 were isolated from this genus for the first time.
Key concepts: Paeonia lactiflora, Paeoniflorin, Gallic acid, Chemistry, Daucosterol, Chromatography, Chemical constituents, Traditional medicine