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A New Phenolic Glucoside from Paeonia lactiflora

HE Xiao-yan, Han Li, Huang Xue-shi

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Abstract

Objective To study the chemical constituents from EtOAc extracts of Paeonia lactiflora. Methods Compounds were isolated by various chromatographic techniques and structures were elucidated on the basis of spectral analysis. Results Seventeen compounds were obtained and their structures were identified as 1,2,6-benzenetriol-1-O-α-D- glucoside (1), paeoniflorin (2), 4-methylpaeoniflorin (3), albiflorin (4), paeonidanin (5), benzoylpaeoniflorin (6), 4-methylbenzoylpaeoniflorin (7), benzoylalbiflorin (8), paeonidanin A (9), galloylalbiflorin (10), debenzoylalbiflorin (11), 4',5-dihydroxyflavanone-7-O-β-D-glucoside (12), 5,7-dihydroxy flavanone-4'-O-β-D-glucoside (13), (+)-catechin (14), gallic acid (15), vanillic acid (16), and 1,2,3-benzenetriol (17). Conclusion Compound 1 is a new compound named paeoniphenoside. Compounds 12 and 13 are firstly obtained from genus Paeonia L., and compounds 5 and 9 are isolated from P. lactiflora for the first time.

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What this paper is about

Objective To study the chemical constituents from EtOAc extracts of Paeonia lactiflora. Methods Compounds were isolated by various chromatographic techniques and structures were elucidated on the basis of spectral analysis. Results Seventeen compounds were obtained and their structures were identified as 1,2,6-benzenetriol-1-O-α-D- glucoside (1), paeoniflorin (2), 4-methylpaeoniflorin (3), albiflorin (4), paeonidanin (5), benzoylpaeoniflorin (6), 4-methylbenzoylpaeoniflorin (7), benzoylalbiflorin (8), paeonidanin A (9), galloylalbiflorin (10), debenzoylalbiflorin (11), 4',5-dihydroxyflavanone-7-O-β-D-glucoside (12), 5,7-dihydroxy flavanone-4'-O-β-D-glucoside (13), (+)-catechin (14), gallic acid (15), vanillic acid (16), and 1,2,3-benzenetriol (17). Conclusion Compound 1 is a new compound named paeoniphenoside. Compounds 12 and 13 are firstly obtained from genus Paeonia L., and compounds 5 and 9 are isolated from P. lactiflora for the first time.

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Available abstract

Objective To study the chemical constituents from EtOAc extracts of Paeonia lactiflora. Methods Compounds were isolated by various chromatographic techniques and structures were elucidated on the basis of spectral analysis. Results Seventeen compounds were obtained and their structures were identified as 1,2,6-benzenetriol-1-O-α-D- glucoside (1), paeoniflorin (2), 4-methylpaeoniflorin (3), albiflorin (4), paeonidanin (5), benzoylpaeoniflorin (6), 4-methylbenzoylpaeoniflorin (7), benzoylalbiflorin (8), paeonidanin A (9), galloylalbiflorin (10), debenzoylalbiflorin (11), 4',5-dihydroxyflavanone-7-O-β-D-glucoside (12), 5,7-dihydroxy flavanone-4'-O-β-D-glucoside (13), (+)-catechin (14), gallic acid (15), vanillic acid (16), and 1,2,3-benzenetriol (17). Conclusion Compound 1 is a new compound named paeoniphenoside. Compounds 12 and 13 are firstly obtained from genus Paeonia L., and compounds 5 and 9 are isolated from P. lactiflora for the first time.

Key concepts: Paeonia lactiflora, Paeoniflorin, Glucoside, Chemistry, Gallic acid, Catechin, Vanillic acid, Chromatography

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