Long-term Domestic Noninvasive Ventilation Function for Chronic Obstructive Pulmonary Disease Treatment

Objective To explore the clinical effects of long-term home noninvasive ventilation on chronic obstructive pulmonary disease(COPD)patients at stable age.Methods 90 cases of COPD patients with acute exacerbations in our hospital were selected and divided into two groups,45 cases in the control group received general treatment at stable stage after discharge,45 cases in the test groupreceived long-term home noninvasive ventilation on the basis of control group treatment.The patients were followed up for 1 year and regular telephone interviews were done,the two groups were observed and compared at discharge and 1 year referral,including the aspects of respiratory function,blood gas analysis and quality of sleep.Results The FEV1 and FVC of the patients of the two groups at discharged time and 1 year later had no significant differences,the difference between the two groups was not significant either(P0.05).The PaCO2 of the test group and control group 1 year after discharge from hospital were(55.23±3.65)mm Hg and(58.32±3.98)mm Hg,the difference between the two groups was not statistically significant(P0.05).The PO2 and pH of the two groups before and after treatment and between-group difference were not statistically significant(P0.05).The sleep quality(PSQI)score of the test group and control group 1 year after discharge was(7.20±2.08)points and(9.78±3.01)points respectively,the difference was statistically significant(P0.05).Conclusion Long-term home noninvasive positive pressure ventilation based on home oxygen therapy does not have obvious effect on the lung function improvement of COPD patients at stable stage,but can significantly improve hypercapnia and sleep quality,which is of great significance for reducing acute onset number and improve patients' quality of life.