The differences of distributions of HPV subtypes in different cervical lesions

Objective:To explore the distributional difference of HPV subtypes in different cervical lesions.Methods:The data of HPV subtypes detection in 189 cases with cervical lesions were analyzed retrospectively.Results:The total infection rate and mixed infection rate of HPV were 56.1% (106/189) and 24.5% (26/106),respectively;the infection rates of HPV in normal cervical tissues,CIN Ⅰ,CIN Ⅱ,CIN Ⅲ and cervical cancer were 19.1% (12/63),57.9% (22/38),70.5% (31/44),88% (22/25) and 100% (19/19),respectively;the main infective subtypes of HPV were 52,58,53,16 and 33 in normal cervical tissues,52,58,16,33 and 18 in CIN Ⅰ,52,16,58,33 and 18 in CIN Ⅱ,16,52,58,33 and 18 in CIN Ⅲ,16,18,52,58 and 33 in cervical cancer,respectively.Conclusion:The distribution frequencies of high-risk HPV subtypes in different cervical lesions from high to low are 16,52,58,33 and 18,respectively,differential infection reflects the potential capability of prognosis.