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2011•Chinese Journal of Gastroenterology and HepatologyRequires access

Effect of portal vein thrombosis on the course of liver cirrhosis

Liwen Kong

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Abstract

Objective To investigate the effect of portal vein thrombosis(PVT) on nature course of liver cirrhosis(LC).Methods Patients with LC during 2003～2011 were reviewed,eighteen cases of LC with PVT,nineteen cases of LC patients without PVT were chosen.The average diameter of main portal vein(MPV),spleen thickness,the stomach esophagus varicosity,ascites etc were compared between the two groups.Results Width of the portal vein and spleen thickness were greater in study group than those in the control group(P0.05).Compared with control group,more severe esophageal varies,higher rate of sever variceal haemorrhage and larger volume of ascites after portal vein thrombosis were shown in the study group(P0.05).Conclusion The splenomegaly and broadening of portal vein are the main risk factors caused PVT,which further increase portal hypertension and the risk of gastrointestinal bleeding.

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What this paper is about

Objective To investigate the effect of portal vein thrombosis(PVT) on nature course of liver cirrhosis(LC).Methods Patients with LC during 2003～2011 were reviewed,eighteen cases of LC with PVT,nineteen cases of LC patients without PVT were chosen.The average diameter of main portal vein(MPV),spleen thickness,the stomach esophagus varicosity,ascites etc were compared between the two groups.Results Width of the portal vein and spleen thickness were greater in study group than those in the control group(P0.05).Compared with control group,more severe esophageal varies,higher rate of sever variceal haemorrhage and larger volume of ascites after portal vein thrombosis were shown in the study group(P0.05).Conclusion The splenomegaly and broadening of portal vein are the main risk factors caused PVT,which further increase portal hypertension and the risk of gastrointestinal bleeding.

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Available abstract

Objective To investigate the effect of portal vein thrombosis(PVT) on nature course of liver cirrhosis(LC).Methods Patients with LC during 2003～2011 were reviewed,eighteen cases of LC with PVT,nineteen cases of LC patients without PVT were chosen.The average diameter of main portal vein(MPV),spleen thickness,the stomach esophagus varicosity,ascites etc were compared between the two groups.Results Width of the portal vein and spleen thickness were greater in study group than those in the control group(P0.05).Compared with control group,more severe esophageal varies,higher rate of sever variceal haemorrhage and larger volume of ascites after portal vein thrombosis were shown in the study group(P0.05).Conclusion The splenomegaly and broadening of portal vein are the main risk factors caused PVT,which further increase portal hypertension and the risk of gastrointestinal bleeding.

Key concepts: Medicine, Cirrhosis, Ascites, Portal vein thrombosis, Portal hypertension, Esophageal varices, Thrombosis, Portal venous pressure

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