The causes and prevention of portal vein thrombosis after splenectomy in patients with hepatitis and cirrhosis

Objective To analyze the relevant factors and explore methods for prevention of portal vein thrombosis in patients after spleuectomy of portal hypertension due to cirrhosis resulted from hepatitis.Methods Clinical data of 143 patients with splenectomy weft analyze,and the relationship of portal system thrombosis with gender,age,temperature,diameter of spleen vein,average diameter of main portal vein,size of spleen,thickness of spleen and number of thrombocytes after operation were compared.Results The results showed that the rate of portal hypertension was 9.79％.The thrombosis of portal vein was related to the average diameter of main portal vein,size of spleen,thickness of spleen and number of thrombocytes after operation (P ＜ 0.05),other than related to the gender,age,temperature and the diameter of spleen vein (P ＞ 0.05).Conclusion The portal vein thrombosis in patients after splenectomy is related to portal vein,diameter of spleen vein and size of the spleen.Anticoagulation therapy given in the early stage can prevent the occurrence of the portal system thrombosis in patients with liver cirrhosis and portal hypertension after splenectomy. Key words: Cirrhosis;  Splenectomy;  Portal vein;  Thrombus