Clinical study of the analgesic effect and security of the combined application of dolantin with diazepam to induced abortion

Objective:To investigate the analgesic effect and security of the combined application of dolantin with diazepam to the artificial termination of pregnancy.Methods:150cases of early pregnancy were randomized into 3groups with 50cases in each group:Group A,B and C.All patients were placed 400μg of misoprostol tablets into the vagina before operations.Group A were performed artificial abortion operation under intravenous anesthesia by fentanyl combined with propofol;Group B were applied dolalntin combined with diazepam to the artificial termination of pregnancy;while Group C(the control group)used oral consolation only.The analgesic effect,operation time,success rate of cervical dilatation,and adverse reaction rate of the three groups were record-ed.Also the HR,MAP,SpO2and RR before operation(T0),at cervical dilatation(T1),and suction and scraping the uterine cavities(T2)were recorded.Results:1.Compared with patients in Group C,patients in Group A and B needed shorter operation time and had high success rate of cervical dilatation,and high postoperative satisfaction score and oral analgesic score(P0.05);2. HR,MAP and RR of Group A and B at between T1and T2 were lower than those in Group C;3. Compared with Group C,the incidence of abortion syndrome of Group A and B was lower(P0. 05).And the incidence rate of abdominal muscle stiffness and glossocoma in Group A was higher. Conclusion:Dolantin combined with diazepam shows an excellent analgesic effect and less adverse reactions in induced abortion.So it is a kind of safe and effective analgesic method in induced abortion.