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Clinical value of combined detection of 4 kinds of tumor markers in diagnosing ovarian cancer

Bin Xiang

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Abstract

Objective To investigate the clinical significance of serum levels of CEA,CA19-9,CA-125 and CA-153 in diagnosing ovarian cancer.Methods The levels of CEA,CA19-9,CA-125 and CA-153 in 49 patients with ovarian cancer,48 patients with benign ovarian tumor and 40 healthy controls were measured by chemistry luminescence immunoassay method.Results The serum levels of CEA,CA19-9,CA-125 and CA-153 in the ovarian cancer group were significantly higher than those in the benign ovarian tumor group and healthy controls.The sensitivity of combination detection of the four markers was higher than that of single item.Conclusion Detection of CEA,CA19-9,CA-125 and CA-153 has certain diagnostic valus to ovarian cancer.The clinical value can be improved by combined detection of the four markers.

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What this paper is about

Objective To investigate the clinical significance of serum levels of CEA,CA19-9,CA-125 and CA-153 in diagnosing ovarian cancer.Methods The levels of CEA,CA19-9,CA-125 and CA-153 in 49 patients with ovarian cancer,48 patients with benign ovarian tumor and 40 healthy controls were measured by chemistry luminescence immunoassay method.Results The serum levels of CEA,CA19-9,CA-125 and CA-153 in the ovarian cancer group were significantly higher than those in the benign ovarian tumor group and healthy controls.The sensitivity of combination detection of the four markers was higher than that of single item.Conclusion Detection of CEA,CA19-9,CA-125 and CA-153 has certain diagnostic valus to ovarian cancer.The clinical value can be improved by combined detection of the four markers.

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Available abstract

Objective To investigate the clinical significance of serum levels of CEA,CA19-9,CA-125 and CA-153 in diagnosing ovarian cancer.Methods The levels of CEA,CA19-9,CA-125 and CA-153 in 49 patients with ovarian cancer,48 patients with benign ovarian tumor and 40 healthy controls were measured by chemistry luminescence immunoassay method.Results The serum levels of CEA,CA19-9,CA-125 and CA-153 in the ovarian cancer group were significantly higher than those in the benign ovarian tumor group and healthy controls.The sensitivity of combination detection of the four markers was higher than that of single item.Conclusion Detection of CEA,CA19-9,CA-125 and CA-153 has certain diagnostic valus to ovarian cancer.The clinical value can be improved by combined detection of the four markers.

Key concepts: Ovarian cancer, CA19-9, Tumor marker, CA 15-3, Medicine, Internal medicine, Immunoassay, Cancer antigen

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