2008Xinjiang nongye kexueRequires access

Detection on Immunity Antibodies and Dynamics of the Egg-type Chicken Immunized with Avian Influenza Vaccine

FU Zi-hua

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Abstract

The experiment was conducted to detect the effect of six different Avian influenza vaccines which was inoculated to the egg-type chickens.The total of 13700 of hens were divided into six groups,in which each group was inoculated with the six different Avian influenza vaccines individually.The both of H5 antibody and H9 antibody were detected by hemagglutination inhibition test in every two weeks.The results indicated that the H5 antibody titers of HVK-2,SDYB and ZZZM were above 4log2 at the second week after inoculation,the H5 antibody titers of CDJH and HVK-1 approached 4log2 and reached the peak at the fourth week then declined gradually.The H5 antibody was hardly detected in the group of HVK-3.The H9 antibody titers were above 5log2 after two weeks of immunization,meanwhile H9 antibody titers all were higher than H5 antibody titers.The 5 groups of hens were immunized with AI vaccine for two times,the H5 antibody titers were higher than the first after the secondary immunization,and the H5 antibody duration was extended obviously.

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What this paper is about

The experiment was conducted to detect the effect of six different Avian influenza vaccines which was inoculated to the egg-type chickens.The total of 13700 of hens were divided into six groups,in which each group was inoculated with the six different Avian influenza vaccines individually.The both of H5 antibody and H9 antibody were detected by hemagglutination inhibition test in every two weeks.The results indicated that the H5 antibody titers of HVK-2,SDYB and ZZZM were above 4log2 at the second week after inoculation,the H5 antibody titers of CDJH and HVK-1 approached 4log2 and reached the peak at the fourth week then declined gradually.The H5 antibody was hardly detected in the group of HVK-3.The H9 antibody titers were above 5log2 after two weeks of immunization,meanwhile H9 antibody titers all were higher than H5 antibody titers.The 5 groups of hens were immunized with AI vaccine for two times,the H5 antibody titers were higher than the first after the secondary immunization,and the H5 antibody duration was extended obviously.

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Available abstract

The experiment was conducted to detect the effect of six different Avian influenza vaccines which was inoculated to the egg-type chickens.The total of 13700 of hens were divided into six groups,in which each group was inoculated with the six different Avian influenza vaccines individually.The both of H5 antibody and H9 antibody were detected by hemagglutination inhibition test in every two weeks.The results indicated that the H5 antibody titers of HVK-2,SDYB and ZZZM were above 4log2 at the second week after inoculation,the H5 antibody titers of CDJH and HVK-1 approached 4log2 and reached the peak at the fourth week then declined gradually.The H5 antibody was hardly detected in the group of HVK-3.The H9 antibody titers were above 5log2 after two weeks of immunization,meanwhile H9 antibody titers all were higher than H5 antibody titers.The 5 groups of hens were immunized with AI vaccine for two times,the H5 antibody titers were higher than the first after the secondary immunization,and the H5 antibody duration was extended obviously.

Key concepts: Antibody, Influenza A virus subtype H5N1, Antibody titer, Inoculation, Titer, Immunization, Virology, Hemagglutination assay

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