Analysis on Serological Markers of HBV Among Urban Residents of Chengdu City

Objective To analyze the positive results of HBVm (serological markers of HBV) and its distribution and possible influential factors from physical examination among residents in urban area of Chengdu City,so as to improve the cognizing ability of common people to hepatitis B infection. and to enrich the people's immune sense to hepatitis B. Method Testing of HBsAg,HBsAb,HBeAg,HBeAb and HBcAb as well as liver function were carried out among 108 685 people in urban area of Chengdu City who took physical examinations in the Physical Examination Center of Sichuan Provincial Hospital from July 1,2007 to June 30,2008. Meantime,the past history,family history,vaccinating history of hepatitis B virus(HBV)infection were investigated. Results The results (No.person and percentage)were as follows:HBVm negative 31 063,28.58%,HBsAg/HBeAg/HBcAb positive 4 637,4.27% ;HBsAg/HBeAb/HBcAb positive 5 250,4.83%,HBsAg/HBcAb positive 527,0.48%,sing'le HBsAb positive 51 228,47.13%,HBsAb/HBeAb/HBcAb positive 1921,1.77%,HBsAb/HBcAb positive 13 200,12.15%,and others (HBeAb/HBcAb positive,only HBeAb positive or only HBcAb positive) 896,abnormal rate 0.82%. Abnormal liver function (single higher transaminase and/or double higher transaminase) revealed in 896 Persons with an abnormal rate of 0.82%. Vaccinating of hepatitis B virus(HBV) was conducted in 33 779 persons with a,vaccinating rate of 31.08%.Conclusion In urban area of Chengdu city,HBsAg carriers and HBsAg positive rate is close to national average level. But vaccinating rate of HBV would be relatively low. To strengthen health education on HBV and to expand the vaccinating rate of HBV,is the most effective method to further decrease the infection rate of hepatitis B virus.