THE INFECTION OF HBV AND THE EFFECT OF HBV VACCINE IN CHILDREN AGED FROM HALF A YEAR TO 6 YEARS IN SHENZHEN

[Objective] To analyze the infection of HBV and the effect of HBV vaccine in children aged from half a year to 6 years,and to provide data for HBV prevention and control in Shenzhen.[Methods] HBV-M among 2 955 children's serum was detected by ELISA.[Results] The positive ratio of HBsAg,HBsAb,HBeAg,HBeAb and HBcAb were 0.95%,76.45%,0.74%,0.61% and 1.25%,respectively;There was no significant difference between the positive ratio of boys and girls.HBV-M among 668(22.61%) children was negative completely.There were 7 positive combined mode of HBV-M as a whole,including 22(0.74%) cases with 'HBsAg+HBeAg+HBcAb',5(0.17%) cases with 'HBsAg+HBeAb+HBcAb',1(0.03%) case with 'HBsAg+HBeAg',2236(75.67%) cases with HBsAb positive alone,5(0.17%) cases with 'HBsAb+ HBeAb',6(0.20%) cases with 'HBsAb+ HBeAb+ HBcAb' and 12(0.41%) cases with 'HBsAb + HBcAb'.[Conclusion] For so many floating population,it is difficult to prevent and control the Hepatitis B in Shenzhen.After compulsive injection of HBV vaccine,the situation of HBV infection becomes better than before,but some measures must be taken to improve the effect of HBV vaccine.