Analysis of correlated factors of the serum prostate specific antigen in the benign prostatic hyperplasia patients with acute urinary retention

Objective:To study the correlated factors of the serum prostate specific antigen (PSA) in the benign prostatic hyperplasia (BPH) patients with acute urinary retention(AUR).Menthods:A total of 260 cases of men with benign prostate hyperplasia were retrospectively studied,and patients with prostatic cancer were excluded.The age,the serum prostate specific antigen and acute urinary retention were recorded,and prostate volume were measured by transabdominal ultrasonography.These variables were correlated with the results from AUR of BPH study. There were 123 cases of benign prostate hyperplasia with acute urinary retention and 137 cases without acute urinary retention.Results:In the group of acute urinary retention, the mean age was (73.30 ±9.59) years,the mean prostatic volume was (58.18 ±36.66)ml, the mean the serum PSA (10.39±10.78)μg/L;In the group of without acute urinary retention, the mean age was (72.04 ±9.19) years,the mean prostate volume was (43.51±23.45)ml,the mean the serum PSA (4.35±4.96)μg/L.There were statistically significant differences between the two groups in prostate volume and PSA(all P0.01).In the different prostate volumes (PV30ml,PV=30～50 ml(all P0.05),PV50 ml),there were statistically significant differences between the two groups in the serum PSA and prostate volume(PV50 ml), and in PV30 ml and PV=30～50 ml,there was no statistically significant difference between the two group in prostate volume(P0.05).There was no obvious difference incidence of AUR between the two group in the serum PSA in 4～10 μg/L(P0.05),and statistically significant different incidence of AUR between the two group in the serum PSA10 μg/L(P0.05).In the benign prostatic hyperplasia with acute urinary retention patients,the serum PSA was positively correlated to prostate volume and the age(P0.01),prostate volume was positively correlated to the age(P0.05).Conclusion:Among these related factors affecting serum PSA,not only prostate volume and age,but also acute urinary retention itself plays a role in AUR of BPH.