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[Optimizing the best extraction condition of semi-bionic extraction for licorice by unifrom design].

Yanqin Cheng, Xiumei Sun, Zhang Zhao-wang, Jian-Guo Hui

Abstract

OBJECTIVE: To optimize the best extraction condition of semi-bionic extraction for licorice. METHODS: The best extraction condition of the semi-bionic extraction for licorice by uniform design was optimized with glycyrrhizic acid, total flavonoids, total polysaccharides, total HPLC integrate area and dried extract weight as the indexes. RESULTS: The optimized technologic condition: The pH values of the water for the 1st, 2nd, and 3rd decoctions were in order of 5.88, 7.50, and 8.90, and the total extraction time was 3.93 h. CONCLUSION: According to industry production condition, the best SBE technologic condition is: The pH values of the water for the 3 decoctions are in order of 6.0, 7.5, and 9.0, and the extraction time are 2h, 1h, and 1h, respectively.

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Available abstract

Key concepts: Decoction, Extraction (chemistry), Chromatography, Water extraction, Chemistry, High-performance liquid chromatography, Traditional medicine, Medicine