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Clinical observation of curative effect of rosiglitazone combined with metformin in type 2 diabetes

BI Lamei

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Abstract

Objective To study the curative effect of rosiglitazone combined with metformin in the treatment of type 2 diabetes.Methods 65 outpatients were randomly divided into two groups.The tested group with 35 patients were treated with rosigilitazone and metformin,while the contrast group with 30 patients were treated with rosigilitazone solely.Observe all patients’ FBG、FINS、DBP、 SBP and IRI of before treatment and 12 weeks after treatment.Results The FBG、FINS and BP of two groups had been descend after treatment(P 0.05) .The descending extent of the tested group's FBG、FINS、DBP、SBP and IRI were higher than the contrast group,and there were statistically significant difference between the two groups(P 0.05) .There were no harm to liver and kidney of all patients.Conclusion Using rosiglitazone with metformin in the treatment of type 2 diabetes,can ameliorate IR and reduce BP of patients,and the curative effect is far better than that only with rosiglitazone.

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What this paper is about

Objective To study the curative effect of rosiglitazone combined with metformin in the treatment of type 2 diabetes.Methods 65 outpatients were randomly divided into two groups.The tested group with 35 patients were treated with rosigilitazone and metformin,while the contrast group with 30 patients were treated with rosigilitazone solely.Observe all patients’ FBG、FINS、DBP、 SBP and IRI of before treatment and 12 weeks after treatment.Results The FBG、FINS and BP of two groups had been descend after treatment(P 0.05) .The descending extent of the tested group's FBG、FINS、DBP、SBP and IRI were higher than the contrast group,and there were statistically significant difference between the two groups(P 0.05) .There were no harm to liver and kidney of all patients.Conclusion Using rosiglitazone with metformin in the treatment of type 2 diabetes,can ameliorate IR and reduce BP of patients,and the curative effect is far better than that only with rosiglitazone.

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Available abstract

Objective To study the curative effect of rosiglitazone combined with metformin in the treatment of type 2 diabetes.Methods 65 outpatients were randomly divided into two groups.The tested group with 35 patients were treated with rosigilitazone and metformin,while the contrast group with 30 patients were treated with rosigilitazone solely.Observe all patients’ FBG、FINS、DBP、 SBP and IRI of before treatment and 12 weeks after treatment.Results The FBG、FINS and BP of two groups had been descend after treatment(P 0.05) .The descending extent of the tested group's FBG、FINS、DBP、SBP and IRI were higher than the contrast group,and there were statistically significant difference between the two groups(P 0.05) .There were no harm to liver and kidney of all patients.Conclusion Using rosiglitazone with metformin in the treatment of type 2 diabetes,can ameliorate IR and reduce BP of patients,and the curative effect is far better than that only with rosiglitazone.

Key concepts: Medicine, Rosiglitazone, Metformin, Type 2 diabetes, Internal medicine, Diabetes mellitus, Gastroenterology, Endocrinology

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