The infection and antibiotic resistance of Pseudomonas aeruginosa

Objective This study was aimed at analyzing the clinical distribution and the trend of bacterial resistance of Pseudomonas aeruginosa in our hospital. Methods we analyzed 355 strains Pseudomonas aeruginosa isolated from 2001 to 2003. The minimum inhibitory concentration(MIC) of 12 antimicrobial agents against Pseudomonas aeruginosa was examined by Walkaway40. Results was assessed according to NCCLS 2002. Results The resistance rates of Pseudomonas aeruginosa to amikacin, tobromycin, imipenem were fairly low. The resistance rates of Pseudomonas aeruginosa to ciprofloxacin, cefepime, ceftazidim, piperacillin/tazobactam, gentamicin were also low. But the resistance rates of Pseudomonas aeruginosa to other antimicrobial agents were higher than 40%. Conclusion The bacterial resistance of Pseudomonas aeruginosa is still or even a more serious clinical problem than before. It is important and urgent to monitor the bacterial resistance of Pseudomonas aeruginosa.