Effective observation on termination of early pregnancy by compound mifepristone combined with misoprostol

Objective To observe the clinical effect of compound mifepristone combined with misoprostol on termination of early pregnancy.Methods 121 women of early pregnancy were divided randomly into two groups,observation group taking compound mifepristone combined with misoprostol,while control group taking mifepristone combined with misoprostol.The time of gestational sac discharge,bleeding post-abortion,the complete abortion rate and side effects were compared.Results Compared with the control group,the complete abortion rate in observation group were higher(95.0% vs 88.5%),the failure rate were lower(1.7% vs 4.9%),but there were no obvious difference between two groups(P0.05).The time of gestational sac discharge in observation group were significantly shorter than control group[(3.6±1.3)h vs(4.2±1.5)h](P0.05),the time of bleeding post-abortion in observation group were obviously shorter than control group[(11.6±3.5)h vs(16.5±4.6)h](P0.01).There were no significant difference in rate of side effects between two groups(P0.05).Conclusion Compound mifepristone combined with misoprostol is effective,safe and convenient on termination of early pregnancy,it can decrease bleeding post-abortion.